An ex-military doctor finds herself in a deadly battle for survival when the Irish mafia seize control of the hospital at which she works. When her son is taken hostage, she is forced to rely upon her battle-hardened past and lethal skills after realizing there's no one left to save the day but her.

影片改编自Garth Stein所著同名畅销小说，聚焦一只名叫恩佐的狗狗，和他的主人——职业赛车手Denny Swift，恩佐跟着Denny学会了很多生活哲学。